The Arthur and Sonia Labatt Brain Tumour Research Centre Biobank, Canada

Certification Status: Approved

Registration Status: Completed

Objective: The BTRC Biobank is a virtual and physical biobank for the study of paediatric central nervous system tumours. Our repository of tumour tissues and associated blood/derivative samples support ongoing research at SickKids, as well as local and international collaborations.

Registered Biobank Name	The Arthur and Sonia Labatt Brain Tumour Research Centre Biobank
Biobank Leader	Andrew Bondoc
Country	Canada
Email for biobank inquiries	andrew.bondoc@sickkids.ca
Principal Investigator	Dr. Peter Dirks
Website	http://www.sickkids.ca/Research/BTRC/Biobank/index.html
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper	Oligo - Collection aimed at supporting several research projects, a research group or a research consortium

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).