DASMAN DIABETES BIOBANK, Saudi Arabia

Registration Status: Completed

Objective: The National Dasman Diabetes Biobank (NDDB) provide DDI and collaborative project investigators with a variety of repository services for conducting short and long-term research projects (epigenetics, clinical trial and prospective) related to diabetes and its complications. The NDDBâ€™s wide range of services including, but not limited to sample processing, sample fractionation (aliquot), storage, testing as well as nucleic acid isolation. NDDB consists of biosafety level 3 with ample laboratory space for blood and other body fluid processing, tissue sample processing (histology and immunohistochemistry lab) and cell culture lab. NDDB is facilitated with secured sample storage rooms with -80Â° C freezers and liquid nitrogen tanks. NDDB house more than 32,000 research participants and manages more than 300,000 biological specimens using a sample management system, Tissue Auditor (Infonetica Research Solutions, United Kingdom) for freezer inventory and tracking. More than 60 research projects (research and medical division) are currently using NDDB services.

Registered Biobank Name	DASMAN DIABETES BIOBANK
Biobank Leader	DEVARAJAN SRIRAMAN
Country	Saudi Arabia
Email for biobank inquiries	sriraman.devarajan@dasmaninstitute.org
Principal Investigator	DR. MOHAMED ABU-FARHA
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).