NOSi, Canada

Registration Status: Completed

Objective: The purpose of this study is to determine if Nitric Oxide Sinus irrigation (NOSi) rinse is effective as a treatment for Biofilm-Associated Recalcitrant Chronic Rhinosinusitis as compared to a standard of care control. Collection of samples for biomarker research is also part of this study.Samples will be stored and analysis will be performed on biomarker variants thought to play a role in sinusitis including, but not limited to, specific candidate genes/genome-wide analysis for RNA, serum analytes, or tissue biomarkers to evaluate their association with observed clinical responses to NOSi. This blood may be used for further cytokine/chemokine evaluation, if needed to determine safety, of the Investigational Medicinal Product (IMP)

Registered Biobank Name NOSi
Biobank Leader Athenea Pascual
Country Canada
Email for biobank inquiries atheneapascual@gmail.com
Principal Investigator Amin Javer
Website
User Type
  • Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties
  • Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group
  • Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper
Biospecimen Collected:
Cohort Highlights