STTBI , Canada

Certification Status: Documents Required

Registration Status: Completed

Objective: The goal of this study is to collect tumour and normal tissue, blood (plasma/serum/buffy coat), skin samples, and bone marrow from patients who are diagnosed with a solid tumour (excluding primary brain) and treated at SickKids. These specimens will be stored in an established long-term repository at SickKids that can be made readily available to conduct future laboratory-based investigations, including clinical, basic, and translational research.

Registered Biobank Name	STTBI
Biobank Leader	Ledia Brunga
Country	Canada
Email for biobank inquiries	ledia.brunga@sickkids.ca
Principal Investigator	David Malkin
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper	Oligo - Collection aimed at supporting several research projects, a research group or a research consortium

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).