Primary CNS brain tumors biobank (bioanque sur les tumeurs primaires du systÃ¨me nerveux central), Canada

Registration Status: Pending

Objective: Every year, about 3000 canadians receive a diagnosis of primary CNS tumor, of which gliomas are the majority. Other primary CNS tumors include meningiomas, neuronal tumors, embryonal tumors and pineal region tumors. In adults, the vast majority of gliomas are malignant and incurable. To better understand these tumors, their molecular-genetic basis, their behavior and their response to treatment, and ultimately to provided improved care to patients, this biobank has been created.

Registered Biobank Name	Primary CNS brain tumors biobank (bioanque sur les tumeurs primaires du systÃ¨me nerveux central)
Biobank Leader	Sarah lapointe
Country	Canada
Email for biobank inquiries	sarah.lapointe.med@ssss.gouv.qc.ca
Principal Investigator	Sarah Lapointe
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).