Early Stage Lung Biobank, Canada

Registration Status: Completed

Objective: The purpose of the BC Lung Biobank is to facilitate investigation of the cause, development, diagnosis and treatment of lung diseases. Samples and their linked information will be made available to researchers who are conducting research projects that aim to improve our overall understanding of these diseases. The samples will be used to investigate lung diseases including genetic (meaning related to genes or hereditary), immunologic (meaning the immune system or the system your body uses to fight disease) and other factors that influence occurrence, response to therapy, and outcomes, as well as act as a resource for internal Biobank research projects.

Registered Biobank Name	Early Stage Lung Biobank
Biobank Leader	Dr. John Yee
Country	Canada
Email for biobank inquiries	richard.xiang@vch.ca
Principal Investigator	Dr. Anna McGuire
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).