cfDNA in Hereditary And High-Risk Malignancies (CHARM), Canada

Registration Status: Completed

Objective: cfDNA in Hereditary And High-Risk Malignancies (CHARM) is a research initiative that collects longitudinal plasma samples, tumour tissue, genomic/epigenomic data, and clinical data on individuals with a hereditary cancer syndrome, regardless of personal cancer history. Our goal is to improve early cancer detection by developing a blood test to predict cancer development in carriers using circulating DNA.

Registered Biobank Name cfDNA in Hereditary And High-Risk Malignancies (CHARM)
Biobank Leader Julia Sobotka - CHARM Program Manager
Country Canada
Email for biobank inquiries
Principal Investigator Dr. Trevor Pugh
User Type
  • Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties
  • Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group
  • Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper
Biospecimen Collected: